How to measure anti-pollution claims in vitro

In-Cosmetics Global, the leading event in the cosmetic industry, provides an excellent opportunity to suppliers of personal care ingredients to present their latest research and launch new active ingredients. As anti-pollution ingredients are a rising trend this year, Karl Lintner organized a workshop on « The pollution story: really a new trend? ». The workshop was dedicated to the […]

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Cosmetogenomics for dermocosmetics

Last January, the European Center of Dermatology organized the 28th European Dermocosmetology Days in Lyon, France. The congress focused on personalized genomics and epigenetics as the future of dermocosmetics. Here at Syntivia, we frequently study gene regulation in the skin using a wide range of cosmetogenomics tests. This process helps us to better understand the activity of cosmetic […]

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Syntivia combines transparent skin model and 3D skin imaging to study aging

Syntivia recently attended the Skin Physiology International Meeting in the Vichy Palais des Congrès (France) on November 17th and 18th, 2016 to present an innovative method to study effects on human skin.  In a collaborative project with the Institute of Advanced Life Science Technology (ITAV) in Toulouse, Syntivia associates a transparent skin model and high-tech […]

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New 3D skin model for cosmetic in vitro tests

The epidermal spheroid, a new 3D skin model As the cosmetic sector no longer allows the use of animal experiments to validate the effect of compounds, finding intermediate models between monolayer cell cultures and live human organisms has become a central issue. Marine Norlund, Biology Project Manager at Syntivia, has presented her work on a […]

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New 3D skin model to study inflammatory response

SYNTIVIA uses a new 3D skin model, an epidermal spheroid, to evaluate cosmetic and dermatological ingredients. The epidermal spheroid is a unique and patented 3D model that contains the two major cell types of the epidermis, i.e. Normal Human Epidermal Keratinocytes (NHEK) and Normal Human Epidermal Melanocytes (NHEM). The epidermal spheroid faithfully reproduces the organization and functionality of […]

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Atomic Force Microscopy to analyse nail polish

SYNTIVIA analyses nail polish using surface characterization based on Atomic Force Microscopy (AFM). Atomic Force Microscopes provide topography data (such as perceived roughness) and measure the nanomechanical properties of a surface (elasticity, stiffness, adherence). A nail polish containing a new active ingredient has been compared to a nail polish without the ingredient. The AFM analysis allowed to measure and illustrate […]

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SYNTIVIA develops new epidermal spheroid skin model

Syntivia has developed a new epidermal spheroid skin model to test cosmetic and dermatological substances. The model comprises the two main cell types of the epidermis, i.e. Normal Human Epidermal Keratinocytes (NHEK) and Normal Human Epidermal Melanocytes (NHEM). Epidermal spheroids provide a more representative view of the human skin than 2D models, as they arrange the cells of the […]

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